5-dehydro-2-deoxyphosphogluconate aldolase

The enzyme 5-dehydro-2-deoxyphosphogluconate aldolase (EC 4.1.2.29) catalyzes the chemical reaction

5-dehydro-2-deoxy-D-gluconate 6-phosphate ${\displaystyle \rightleftharpoons }$ glycerone phosphate^[1] + malonate semialdehyde

5-dehydro-2-deoxyphosphogluconate aldolase
Identifiers
EC no.	4.1.2.29
CAS no.	62213-25-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming). Other names in common use include phospho-5-keto-2-deoxygluconate aldolase, 5-dehydro-2-deoxy-D-gluconate-6-phosphate, and malonate-semialdehyde-lyase.