6-(Methylsulfinyl)hexyl isothiocyanate

6-(Methylsulfinyl)hexyl isothiocyanate (6-MITC or 6-MSITC) is a compound within the isothiocyanate group of organosulfur compounds. 6-MITC is obtained from cruciferous vegetables, chiefly wasabi. Like other isothiocyanates, it is produced when the enzyme myrosinase transforms the associated glucosinolate into 6-MITC upon cell injury.

6-(Methylsulfinyl)hexyl isothiocyanate

Names
Preferred IUPAC name 1-Isothiocyanato-6-(methanesulfinyl)hexane
Other names 6-MITC; 6-MSITC; Hesperin
Identifiers
CAS Number	4430-35-7 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:138799
ChEMBL	ChEMBL573428
ChemSpider	7991398
PubChem CID	9815648
UNII	8RUP6Q3JBB Y
CompTox Dashboard (EPA)	DTXSID00431173
InChI InChI=1S/C8H15NOS2/c1-12(10)7-5-3-2-4-6-9-8-11/h2-7H2,1H3 Key: XQZVZULJKVALRI-UHFFFAOYSA-N
SMILES CS(=O)CCCCCCN=C=S
Properties
Chemical formula	C8H15NOS2
Molar mass	205.33 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

It is a trend in Japan to apply freshly grated wasabi stem to the hair because Kinin Corporation, the world's largest wasabi producer, claims that 6-MITC promotes hair regrowth.^[1]

In a 2023 study of healthy older adults aged 60 years and over, the group taking one tablet (0.8 mg of 6-MSITC) every day for 12 weeks showed a significant improvement in working and episodic memory performances.^[2] These results have been reported in the popular press, using the name "hexaraphane" for 6-MSITC.^[3]

See also

• Methyl isothiocyanate