PARGY-LAD

PARGY-LAD, also known as 6-propynyl-6-nor-LSD or 6-propargyl-6-nor-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD).^[3]

PARGY-LAD

Clinical data
Other names	PARGYLAD; PROPARGYL-LAD; PROPARGYLLAD; 6-Propynyl-6-nor-LSD; N,N-Diethyl-6-propargyl-6-norlysergamide; N,N-Diethyl-6-(prop-2-yn-1-yl)-9,10-didehydroergoline-8β-carboxamide
Routes of administration	Oral[1]
Drug class	Serotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act Illegal in France[2]
Identifiers
IUPAC name (6aR,9R)-N,N-diethyl-7-prop-2-ynyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
CAS Number	2767597-51-1 Y
PubChem CID	139030999
ChemSpider	21106360 Y
CompTox Dashboard (EPA)	DTXSID501045856
Chemical and physical data
Formula	C22H25N3O
Molar mass	347.462 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)C(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C2)CC#C)c34
InChI InChI=1S/C22H25N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h1,7-9,11,13,16,20,23H,5-6,10,12,14H2,2-3H3/t16-,20-/m1/s1 Y Key:BPJKJUFQSNRQCR-OXQOHEQNSA-N Y
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Use and effects

PARGY-LAD is hallucinogenic similarly to LSD, but is considerably less potent than LSD, with a dose of 160 μg producing only mild effects, and 500 μg required for full activity.^[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

History

PARGY-LAD was developed by David E. Nichols and colleagues at Purdue University in the 1980s^[3] and is described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).^[1]

See also

• Substituted lysergamide