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7-Chlorotryptamine

Pharmaceutical compound From Wikipedia, the free encyclopedia

7-Chlorotryptamine
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7-Chlorotryptamine (7-chloro-T, 7-CT, or 7-Cl-T; code name PAL-532) is a serotonin receptor agonist and monoamine releasing agent (MRA) of the tryptamine family.[1] It is a pale yellow solid.[2] It is a full agonist of the serotonin 5-HT2A receptor, with an EC50Tooltip half-maximal effective concentration of 18.8 nM and an EmaxTooltip maximal efficacy of 102%.[1] In addition, it is a serotonin releasing agent (SRA), with EC50 values of 8.03 nM for serotonin, 656 nM for norepinephrine, and 1,330 nM for dopamine in rat brain synaptosomes.[1] The drug is one of the most potent SRAs in vitro known, after 6-fluorotryptamine (6-FT) and naphthylaminopropane (NAP; PAL-287).[1] 7-CT was first described in the scientific literature by 2014.[1]

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