8A-PDHQ

8a-Phenyldecahydroquinoline (8A-PDHQ) is a high affinity NMDA antagonist developed by a team at Parke Davis in the 1950s.^[1] It is a structural analog of phencyclidine with slightly lower binding affinity than the parent compound. (−)-8a-Phenyldecahydroquinoline has an in vivo potency comparable to that of (+)-MK-801.^[2][3]

8A-PDHQ

Identifiers
IUPAC name 8a-phenyldecahydroquinoline
CAS Number	131556-11-1 N
PubChem CID	131397
ChemSpider	116144 Y
UNII	8GBT78N4EC
CompTox Dashboard (EPA)	DTXSID40927262
Chemical and physical data
Formula	C15H21N
Molar mass	215.340 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1([C@]23CCCC[C@H]2CCCN3)=CC=CC=C1
InChI InChI=1S/C15H21N/c1-2-7-13(8-3-1)15-11-5-4-9-14(15)10-6-12-16-15/h1-3,7-8,14,16H,4-6,9-12H2 Y Key:QEXADSRMRUUCQJ-UHFFFAOYSA-N Y
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