AC927

AC927
Identifiers
	IUPAC name 1-(2-phenylethyl)piperidine or N-phenethyl-piperidine;
CAS Number	332-14-9 ;
ChemSpider	9141;
UNII	5TY7C52M7F;
CompTox Dashboard (EPA)	DTXSID5059822 ;
ECHA InfoCard	100.005.785
Chemical and physical data
Formula	C13H19N
Molar mass	189.302 g·mol−1

AC927 or 1-(2-phenylethyl)piperidine is a selective sigma receptor antagonist, with reported binding affinity of K_i = 30 ± 2 nM for the sigma-1 receptor and K_i = 138 ± 18 nM for the sigma-2 receptor, and negligible binding affinity for other major central nervous system receptors, transporters, and ion channels.^[1]

Quick Facts Identifiers, CAS Number ...

AC927 is reported to attenuate the locomotor stimulation induced by methamphetamine in mice.^[1]

References