ADAMTS-4 endopeptidase

ADAMTS-4 endopeptidase (EC 3.4.24.82, aggrecanase-1) is an enzyme.^[1] This enzyme catalyses the following chemical reaction

Glutamyl endopeptidase; bonds cleaved include -Thr-Glu-Gly-Glu³⁷³-Ala-Arg-Gly-Ser- in the interglobular domain of mammalian aggrecan

ADAMTS-4 endopeptidase
Identifiers
EC no.	3.4.24.82
CAS no.	147172-61-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the peptidase family M12.