ADAMTS13 endopeptidase

ADAMTS13 endopeptidase (EC 3.4.24.87, ADAMTS VWF cleaving metalloprotease, ADAMTS-13, ADAMTS13, vWF-cleaving protease, VWF-CP, vWF-degrading protease, Upshaw factor, von Willebrand factor cleaving protease, ADAMTS13 peptidase) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

The enzyme cleaves the von Willebrand factor at bond Tyr⁸⁴²-Met⁸⁴³ within the A2 domain

ADAMTS13 endopeptidase
Identifiers
EC no.	3.4.24.87
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme belong in the peptidase family M12.