AGH-192

AGH-192 is a potent and selective, water soluble, orally bioavailable and brain penetrant full agonist at the 5-HT₇ serotonin receptor of the imidazolylindole family, derived from the older drug AGH-107. In animal tests it showed activity indicative of potential application in the treatment of neuropathic pain.^[1]

AGH-192

Identifiers
IUPAC name 3-(3-ethylimidazol-4-yl)-4-fluoro-5-iodo-1H-indole
CAS Number	2173387-57-8 N[EPA]
PubChem CID	139488606
ChemSpider	127419353
UNII	ZJ3VJS5PM7
ChEMBL	ChEMBL4452569
CompTox Dashboard (EPA)	DTXSID301336542
Chemical and physical data
Formula	C13H11FIN3
Molar mass	355.155 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN1C=NC=C1C2=CNC3=C2C(=C(C=C3)I)F
InChI InChI=1S/C13H11FIN3/c1-2-18-7-16-6-11(18)8-5-17-10-4-3-9(15)13(14)12(8)10/h3-7,17H,2H2,1H3 Key:KBQLQDPQEMFGCB-UHFFFAOYSA-N

See also

• Imidazolylindole
• AGH-107
• AH-494