Apoptosis-inducing factor, mitochondria-associated 3

Apoptosis-inducing factor, mitochondria-associated 3 is a protein that in humans is encoded by the AIFM3 gene.^[5]

AIFM3
Identifiers
Aliases	AIFM3, AIFL, apoptosis inducing factor, mitochondria associated 3, apoptosis inducing factor mitochondria associated 3
External IDs	OMIM: 617298; MGI: 1919418; HomoloGene: 13773; GeneCards: AIFM3; OMA:AIFM3 - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q11.21 Start 20,965,108 bp[1] End 20,981,360 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 A3 Start 17,489,611 bp[2] End 17,507,485 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon right frontal lobe right hemisphere of cerebellum cingulate gyrus anterior cingulate cortex Brodmann area 9 caudate nucleus amygdala nucleus accumbens putamen Top expressed in cerebellar cortex Epithelium of choroid plexus primary visual cortex habenula superior frontal gyrus cerebellar vermis lobe of cerebellum facial motor nucleus inferior colliculi nucleus of stria terminalis More reference expression data BioGPS n/a
Gene ontology Molecular function iron-sulfur cluster binding oxidoreductase activity metal ion binding flavin adenine dinucleotide binding 2 iron, 2 sulfur cluster binding Cellular component mitochondrial inner membrane endoplasmic reticulum mitochondrion nucleus cytosol Biological process execution phase of apoptosis apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 150209 72168 Ensembl ENSG00000183773 ENSMUSG00000022763 UniProt Q96NN9 Q3TY86 RefSeq (mRNA) NM_001018060 NM_001146288 NM_144704 NM_001386814 NM_001291070 NM_175178 RefSeq (protein) NP_001018070 NP_001139760 NP_653305 NP_001277999 NP_780387 Location (UCSC) Chr 22: 20.97 – 20.98 Mb Chr 16: 17.49 – 17.51 Mb PubMed search [3] [4]
Wikidata
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