ASP2535

ASP2535 is an inhibitor of the type 1 glycine transporter.^[1] It could potentially be used in treatment of Alzheimer's disease and schizophrenia.

ASP2535

Names
IUPAC name 4-[3-(6-phenylpyridin-3-yl)-5-propan-2-yl-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole
Identifiers
CAS Number	374886-51-8
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL4303475
PubChem CID	9800113
UNII	6627LI8F9K
InChI InChI=1S/C22H18N6O/c1-14(2)21-24-25-22(28(21)19-10-6-9-18-20(19)27-29-26-18)16-11-12-17(23-13-16)15-7-4-3-5-8-15/h3-14H,1-2H3 Key: FQGLDGKVKDPVLO-UHFFFAOYSA-N
SMILES CC(C)C1=NN=C(N1C2=CC=CC3=NON=C32)C4=CN=C(C=C4)C5=CC=CC=C5
Properties
Chemical formula	C22H18N6O
Molar mass	382.427 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Potential uses

ASP2535 has been investigated for the treatment of Alzheimer's disease and schizophrenia, it is able to inhibit the memory deficit induced by scopolamine, an anticholinergic agent.^[1]