Actino-pnp RNA motif

The Actino-pnp RNA motif is a conserved structure found in Actinomycetota that is apparently in the 5' untranslated regions of genes predicted to encode exoribonucleases.^[1] The RNA element's function is likely analogous to an RNA structure found upstream of polynucleotide phosphorylase genes in E. coli and related enterobacteria.^[2] In this latter system, the polynucleotide phosphorlyase gene regulates its own expression levels by a feedback mechanism that involves its activity upon the RNA structure. However, the E. coli RNA appears to be structurally unrelated to the Actino-pnp motif.

Actino-pnp RNA
Consensus secondary structure of Actino-pnp RNAs
Identifiers
Symbol	Actino-pnp
Rfam	RF01688
Other data
Domain(s)	Bacteria
SO	0005836
PDB structures	PDBe