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Adenosquamous carcinoma
Medical condition From Wikipedia, the free encyclopedia
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Adenosquamous carcinoma is a type of cancer that contains two types of cells: squamous cells (thin, flat cells that line certain organs) and gland-like cells. It has been associated with more aggressive characteristics when compared to adenocarcinoma in certain cancers.[1][2] It is responsible for 1% to 4% of exocrine forms of pancreas cancer.[3]
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Diagnosis

Light microscopy shows a combination of gland-like cells and squamous epithelial cells.[4] On immunohistochemistry, it is typically positive for CK5/6, CK7 and p63, and negative for CK20, p16 and p53. On genetic testing, KRAS and p53 are typically altered.[4]
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External links
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