Aildenafil

Aildenafil (methisosildenafil) is a synthetic drug that is a structural analog of sildenafil (Viagra).^[1] It was first reported in 2003.^[2] Like sildenafil, aildenafil is a phosphodiesterase type 5 inhibitor.

Aildenafil

Clinical data
Other names	Methisosildenafil; Dimethyl sildenafil
Legal status
Legal status	In general, unapproved and unscheduled; Rx in China
Identifiers
IUPAC name 5-[5-[(3S,5R)-3,5-dimethylpiperazin-1-yl]sulfonyl-2-ethoxyphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
CAS Number	496835-35-9
PubChem CID	135452876
ChemSpider	8316620
UNII	9T49W8GAX6
CompTox Dashboard (EPA)	DTXSID10197970
Chemical and physical data
Formula	C23H32N6O4S
Molar mass	488.61 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4C[C@H](N[C@H](C4)C)C)OCC)C
InChI InChI=1S/C23H32N6O4S/c1-6-8-18-20-21(28(5)27-18)23(30)26-22(25-20)17-11-16(9-10-19(17)33-7-2)34(31,32)29-12-14(3)24-15(4)13-29/h9-11,14-15,24H,6-8,12-13H2,1-5H3,(H,25,26,30)/t14-,15+ Key:NFSWSZIPXJAYLR-GASCZTMLSA-N

Aildenafil has been found as an adulterant in a variety of supplements which are sold as "natural" or "herbal" sexual enhancement products.^{[3][4][5][6][7]} The United States Food and Drug Administration has warned consumers that any sexual enhancement product that claims to work as well as prescription products is likely to contain such a contaminant.^[8]

Aildenafil is approved for use in China.^[9]

See also

• Acetildenafil
• Nitrosoprodenafil
• Sulfoaildenafil