All-trans-octaprenyl-diphosphate synthase

All-trans-octaprenyl-diphosphate synthase (EC 2.5.1.90, octaprenyl-diphosphate synthase, octaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-heptaprenyltranstransferase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units).^[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate ${\displaystyle \rightleftharpoons }$ 5 diphosphate + all-trans-octaprenyl diphosphate

All-trans-octaprenyl-diphosphate synthase
Identifiers
EC no.	2.5.1.90
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate.