Alpha-humulene synthase

α-Humulene synthase (EC 4.2.3.104,ZSS1) is an enzyme with a systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (α-humulene-forming).^[1] This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate ${\displaystyle \rightleftharpoons }$ α-humulene + diphosphate

α-humulene synthase
Identifiers
EC no.	4.2.3.104
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme from Zingiber zerumbet, can be used to make shampoo ginger. It also gives traces of β-caryophyllene.