Alpha-isocomene synthase

α-Isocomene synthase (EC 4.2.3.136, MrTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (–)-α-isocomene-forming).^[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate ${\displaystyle \rightleftharpoons }$ (–)-α-isocomene + diphosphate

α-isocomene synthase
Identifiers
EC no.	4.2.3.136
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme is isolated from the roots of the plant Matricaria chamomilla var. recutita (chamomile).