Amine oxidase

An amine oxidase is an enzyme that catalyzes the oxidative cleavage of alkylamines into aldehydes and ammonia:^[1]

RCH₂NH₂ + H₂O + O₂ ${\displaystyle \rightleftharpoons }$ RCHO + NH₃ + H₂O₂

Amine oxidases are divided into two subfamilies based on the cofactor they contain:

Class	Cofactor	Subclass	Enzyme Commission number	Human genes
Amine oxidase (formerly EC 1.4.3.6)	copper	lysyl oxidase	EC 1.4.3.13	LOX
		primary-amine oxidase	EC 1.4.3.21	AOC2, AOC3
		diamine oxidase	EC 1.4.3.22	AOC1
Monoamine oxidase	flavin	N/A	EC 1.4.3.4	MAOA, MAOB