Aminopeptidase B

Aminopeptidase B (EC 3.4.11.6, arylamidase II, arginine aminopeptidase, arginyl aminopeptidase, Cl—activated arginine aminopeptidase, cytosol aminopeptidase IV, L-arginine aminopeptidase) is an enzyme.^{[1][2][3][4][5][6]} This enzyme catalyses the following chemical reaction

Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys

Aminopeptidase B
Identifiers
EC no.	3.4.11.6
CAS no.	9073-92-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme from mammalian tissues is activated by chloride ions and low concentrations of thiol compounds.

An inhibitor is bestatin (ubenimex).