Amphinase

Amphinase is a ribonuclease enzyme found in the oocytes of the Northern leopard frog (Rana pipiens). Amphinase is a member of the pancreatic ribonuclease protein superfamily and degrades long RNA substrates.^[2] Along with ranpirnase, another leopard frog ribonuclease, amphinase has been studied as a potential cancer therapy due to its unusual mechanism of cytotoxicity tested against tumor cells.^[3]

Amphinase
Crystallographic structure of amphinase.[1]
Identifiers
Organism	Rana pipiens
Symbol	n/a
PDB	2P7S
UniProt	P85073
Other data
EC number	3.1.27
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