Amygdalin beta-glucosidase

The enzyme amygdalin β-glucosidase (EC 3.2.1.117) catalyzes the following chemical reaction:

(R)-amygdalin + H₂O ${\displaystyle \rightleftharpoons }$ (R)-prunasin + D-glucose

amygdalin β-glucosidase
Identifiers
EC no.	3.2.1.117
CAS no.	51683-43-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are (R)-amygdalin and H₂O, whereas its two products are (R)-prunasin and D-glucose.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is amygdalin beta-D-glucohydrolase. Other names in common use include amygdalase, amygdalinase, amygdalin hydrolase, and amygdalin glucosidase.

It can be completely inhibited by the action of Glucono-δ-lactone at 1 mM concentration.^[1]