Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.^{[citation needed]}

Androgen-dependent condition
Specialty	Endocrinology

Known androgen-dependent conditions include acne,^[1] seborrhea,^[2][3][4] androgenic alopecia,^[5] hirsutism,^[6] hidradenitis suppurativa,^[7] precocious puberty in boys,^[8] hypersexuality,^[9] paraphilias,^[10] benign prostatic hyperplasia (BPH),^[11] prostate cancer,^[12] and hyperandrogenism in women such as in polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), and androgen-secreting tumors (gonadal or adrenal tumor).^[13][14]

Such conditions may be treated with drugs with antiandrogen actions, including androgen receptor antagonists such as cyproterone acetate, spironolactone, and bicalutamide, 5α-reductase inhibitors such as finasteride and dutasteride, CYP17A1 inhibitors such as abiraterone acetate, gonadotropin-releasing hormone (GnRH) analogues such as leuprorelin and cetrorelix, and/or other antigonadotropins such as megestrol acetate and medroxyprogesterone acetate.^[15][16]

See also

• Androgen deprivation therapy
• Androgen insensitivity syndrome
• Estrogen-dependent condition
• Spinal bulbar muscular atrophy