Apocrine nevus

An Apocrine nevus is an extremely rare cutaneous condition that is composed of hyperplastic mature apocrine glands.^[1]: 775 Apocrine nevi present as a nodular skin-coloured lump. They are typically asymptomatic. Apocrine nevi can be congenital and they have been associated with other disorders.

Apocrine nevus
Other names	Apocrine gland hamartoma
Specialty	Medical genetics

Signs and symptoms

Apocrine nevi manifests as a persistent pedunculated or nodular skin-coloured axillary lump.^[2] Additionally, reports of them occurring on the face,^[3][4] scalp,^[5] chest,^[6] and inguinal area have been made.^[7] The majority of the time, apocrine nevi are asymptomatic, although some individuals describe minor pain, baldness, or in rare cases, leakage.^[8][9]

Causes

Apocrine nevi may be congenital.^[9] There have been reported associations with neurofibromatosis,^[6] epilepsy,^[8] and localized dermal hypoplasia, but these may be coincidental.^[10]

Diagnosis

According to histopathology, apocrine nevi are made up of several mature apocrine sweat glands grouped in lobules that invade the dermis and/or hypodermis and cause normal skin structures to be displaced. There may be some cystic dilatation of the lumina in these glands.^[11]

See also

• Eccrine nevus
• Seborrheic keratosis
• List of cutaneous conditions