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Asialoglycoprotein

Class of glycoproteins from which sialic acid has been removed by the action of sialidases From Wikipedia, the free encyclopedia

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If terminal sialic acid residues are removed from glycoproteins, the resulting proteins are known as asialoglycoproteins.[1][2]

In rats, the exposure of subterminal galactose or GalNAc residues may assist in receptor-mediated endocytosis of asialoglycoproteins by asialoglycoprotein receptors on Kuppfer cells. The human ortholog of this gene is non-functional, but hepatocyte asialoglycoprotein receptors are functional in both humans and rats.[3]

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