BDPC

Not to be confused with bromperidol or bromadoline.

BDPC (systematic name 4-(4-bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexanol; also known as bromadol) is a potent fully synthetic opioid with a distinctive arylcyclohexylamine chemical structure. It was developed by Daniel Lednicer at Upjohn in the 1970s.^[1] Initial studies estimated that it was around 10,000 times the potency of morphine in animal models.^[2] However, later studies using more modern techniques assigned a value of 504 times the potency of morphine for the more active trans-isomer.^[3] This drug was first seized along with three kilograms of acetylfentanyl in an April 25, 2013 police action in Montreal, Canada,^[4] and has reportedly continued to be available on the designer drug market internationally.^[5][6] Analogues where the para-bromine is replaced by chlorine or a methyl group retain similar activity, while the meta-hydroxyl derivative demonstrated robust antagonist activity.^[7][8]

p-methyl analogue of BDPC

p-chloro analogue of BDPC.

m-hydroxy analogue of BDPC.

BDPC

Clinical data
ATC code	None
Identifiers
IUPAC name 4-(4-Bromophenyl)-4-(dimethylamino)-1-(2-phenylethyl)cyclohexan-1-ol
CAS Number	77239-98-6 Y 70895-01-1 (HCl)
PubChem CID	9887338
ChemSpider	8063011 Y
UNII	G8HCJ9R4VZ
ChEMBL	ChEMBL3303774
Chemical and physical data
Formula	C22H28BrNO
Molar mass	402.376 g·mol−1
3D model (JSmol)	Interactive image
Melting point	208 to 210 °C (406 to 410 °F)
SMILES CN(C)C1(CCC(CC1)(CCC2=CC=CC=C2)O)C3=CC=C(C=C3)Br
InChI InChI=1S/C22H28BrNO/c1-24(2)22(19-8-10-20(23)11-9-19)16-14-21(25,15-17-22)13-12-18-6-4-3-5-7-18/h3-11,25H,12-17H2,1-2H3 Y Key:PRSUTWWKYIVBEU-UHFFFAOYSA-N Y
(verify)

See also

• 3-HO-PCP
• 4-Keto-PCP
• C-8813
• Cebranopadol
• Ciramadol
• Dimetamine
• Faxeladol
• Profadol
• Tapentadol
• Tramadol