Protein BTG3

Protein BTG3 is a protein that in humans is encoded by the BTG3 gene.^[5][6]

BTG3
Identifiers
Aliases	BTG3, ANA, TOB5, TOB55, TOFA, BTG family member 3, BTG anti-proliferation factor 3, ANA/APRO4
External IDs	OMIM: 605674; MGI: 109532; HomoloGene: 4953; GeneCards: BTG3; OMA:BTG3 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q21.1 Start 17,593,653 bp[1] End 17,612,945 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C3.1 Start 78,129,525 bp[2] End 78,174,080 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone cartilage tissue corpus epididymis ganglionic eminence parotid gland gingival epithelium islet of Langerhans right uterine tube beta cell lower lobe of lung Top expressed in pancreas epiblast lung islet of Langerhans embryo ventricular zone embryo placenta lip ovary More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm nucleus Biological process negative regulation of cell population proliferation negative regulation of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10950 12228 Ensembl ENSG00000281484 ENSG00000154640 ENSMUSG00000022863 UniProt Q14201 Q6IAU3 P50615 RefSeq (mRNA) NM_001130914 NM_006806 NM_001297747 NM_009770 RefSeq (protein) NP_001124386 NP_006797 NP_001124386.1 NP_006797.3 NP_001284676 NP_033900 Location (UCSC) Chr 21: 17.59 – 17.61 Mb Chr 16: 78.13 – 78.17 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system.^[6]