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Balding–Nichols model
Model in population genetics From Wikipedia, the free encyclopedia
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In population genetics, the Balding–Nichols model is a statistical description of the allele frequencies in the components of a sub-divided population.[1] With background allele frequency p the allele frequencies, in sub-populations separated by Wright's FST F, are distributed according to independent draws from
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where B is the Beta distribution. This distribution has mean p and variance Fp(1 – p).[2]
The model is due to David Balding and Richard Nichols and is widely used in the forensic analysis of DNA profiles and in population models for genetic epidemiology.
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References
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