Beclamide

Beclamide (marketed as Chloracon, Hibicon, Posedrine, Nydrane, Seclar, and other names) is a drug that possesses anticonvulsant activity.^[2] It is no longer used.

Beclamide

Clinical data
Routes of administration	By mouth
ATC code	N03AX30 (WHO)
Legal status
Legal status	BR: Class C1 (Other controlled substances)[1]
Identifiers
IUPAC name N-Benzyl-3-chloropropanamide
CAS Number	501-68-8 Y
PubChem CID	10391
ChemSpider	9962 Y
UNII	F5N0ALI65V
KEGG	D07300 Y
ChEMBL	ChEMBL64195 Y
CompTox Dashboard (EPA)	DTXSID5057755
ECHA InfoCard	100.007.207
Chemical and physical data
Formula	C10H12ClNO
Molar mass	197.66 g·mol−1
3D model (JSmol)	Interactive image
Melting point	94 °C (201 °F)
SMILES ClCCC(=O)NCc1ccccc1
InChI InChI=1S/C10H12ClNO/c11-7-6-10(13)12-8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,13) Y Key:JPYQFYIEOUVJDU-UHFFFAOYSA-N Y
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Uses

It has been used as a sedative and as an anticonvulsant.

It was studied in the 1950s for its anticonvulsant properties, as a treatment for generalised tonic-clonic seizures. It was not effective for absence seizures.

Interest in the drug resumed in the 1990s for its psychiatric properties as an adjunct in the treatment of schizophrenia.^[3]

Side effects

Side effects are uncommon but include stomach pain, nervousness, giddiness, skin rash and leukopenia. It is counter-indicated in breast feeding as it is passed in the milk.