Bicine

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C.^[1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.^[2]

Bicine

Names
IUPAC name N,N-Bis(2-hydroxyethyl)glycine
Systematic IUPAC name [Bis(2-hydroxyethyl)amino]acetic acid
Other names Diethylolglycine; Diethanol glycine; Dihydroxyethylglycine; BHG
Identifiers
CAS Number	150-25-4 Y
3D model (JSmol)	Interactive image
Abbreviations	DHEG
ChEBI	CHEBI:39066 Y
ChEMBL	ChEMBL1231251 N
ChemSpider	8431 Y
DrugBank	DB03709 Y
ECHA InfoCard	100.005.233
PubChem CID	8761
UNII	1J484QFI1O Y
CompTox Dashboard (EPA)	DTXSID3041669
InChI InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Y Key: FSVCELGFZIQNCK-UHFFFAOYSA-N Y InChI=1/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Key: FSVCELGFZIQNCK-UHFFFAOYAV
SMILES O=C(O)CN(CCO)CCO
Properties
Chemical formula	C6H13NO4
Molar mass	163.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O₂, SO₂, H₂S or Thiosulfate.^[3]

See also

• Tricine