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Bifidobacterium adolescentis

Species of bacterium From Wikipedia, the free encyclopedia

Bifidobacterium adolescentis
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Bifidobacterium adolescentis is an anaerobic species of bacteria found in the gastrointestinal tracts of humans and other primates.[1] It is one of the most abundant and prevalent Bifidobacterium species detected in human populations, especially in adults.[2][3]

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Research into health benefits

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Bifidobacterium adolescentis has been studied for its health benefits, as strains have been shown to potentially protect against or improve recovery from several diseases, including liver-related,[4] metabolic,[5] allergic airway,[6] colitis,[7] arthritis,[8] and bacterial infections.[9] Strains have also been demonstrated to possess anti-inflammatory,[10] anxiolytic,[11] antioxidant,[12] antidepressant,[13] and/or antiviral[14] activity.

In addition, B. adolescentis strains have been of interest for their ability to metabolize various compounds. This includes prebiotics such as arabinoxylan,[15] XOS,[16] and GOS.[17] Some strains of B. adolescentis are also adept at metabolizing lactose, and may reduce symptoms associated with lactose intolerance.[18] Like other bifidobacteria, B. adolescentis typically produce acetic acid and lactic acid, though the exact ratio depends on the bacterial strain, the carbohydrate being metabolized, and the growth conditions.[19] Production of short chain fatty acids and lactic acid in the colon is associated with health benefits.[20]

Bifidobacterium adolescentis contributes to the production of GABA,[21] a neurotransmitter that plays a role in reducing stress and anxiety. Some B. adolescentis strains can also synthesize B vitamins,[22] such as folic acid.[23] One strain has been shown to be bifidogenic in the GI tract. That is, the presence of one B. adolescentis strain enhances the growth of all bifidobacteria, a group that generally confers positive health benefits[24] and is important for healthy aging.[25]

Some B. adolescentis have been shown to strengthen the intestinal barrier[26] that is important in preventing pathogenic bacteria and toxins from traveling from the gut lumen into the body. Another study suggested the opposite effect: an undefined B. adolescentis strain was observed to disrupt gut barrier functions in colonic epithelial cell cultures.[27]

Multiple probiotics are marked as containing B. adolescentis, however there are a limited number of commercially available strains (PRL2019,[21] iVS1[18][26]) with published scientific studies supporting their health claims.

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References

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