Brisavirus

Brisavirus (isolate LC KY052047) is a species of viruses in the family Redondoviridae in the genus Torbevirus.^[1] Brisa- is from the Spanish word for "Breeze", which refers to their isolation from the human respiratory tract. It was discovered in a throat swab in a male traveler who presented with fever, enlarged adenoids, flushed skin and myalgia after testing negative for other viruses.^[2] Brisavirus like other viruses in the Redondoviridae family, are present and putatively replicate in the oro-respiratory tract.^[3] They are associated in patients with critical illness and periodontitis.^[3]

Brisavirus
Virus classification
(unranked):	Virus
Realm:	Monodnaviria
Kingdom:	Shotokuvirae
Phylum:	Cressdnaviricota
Class:	Arfiviricetes
Order:	Recrevirales
Family:	Redondoviridae
Genus:	Torbevirus
Species:	Torbevirus brisa

Genome

Brisavirus has a CRESS DNA genome with 3 open reading frames that are inversely oriented that encode for the capsid and Replication-associated protein protein with a small and larger intergenic region.^[4] They replicate using rolling-circle replication like other CRESS viruses.^[4] By using metagenomic analysis, researchers found that the encoded proteins were most similar to porcine stool-associated circular virus 5 isolate CP33 (PoSCV5).^[2][3]