Bromal hydrate

Bromal hydrate is an organobromine compound with the chemical formula C₂H₃Br₃O₂. It is the bromine analogue of chloral hydrate. Bromal hydrate forms when bromal is reacted with water. It decomposes to bromal and water upon distillation.^[1] It has hypnotic and analgesic properties but acts like a stimulant at lower doses.^[3] Bromal hydrate is more physiologically active than its chlorine analogue, chloral hydrate.^[4] Its direct effect on the heart muscles is stronger than that of chloral hydrate.^[3] Its analgesic effects were attributed to the proposed metabolism to bromoform.^[5]

Bromal hydrate

Names
IUPAC name 2,2,2-Tribromo-1,1-ethanediol
Other names tribromoethylidene glycol
Identifiers
CAS Number	507-42-6
3D model (JSmol)	Interactive image
ChemSpider	61488
ECHA InfoCard	100.007.340
EC Number	208-073-2
PubChem CID	68181
UNII	BQU83Q7216
CompTox Dashboard (EPA)	DTXSID20198751
InChI InChI=1S/C2H3Br3O2/c3-2(4,5)1(6)7/h1,6-7H Key: NJHVMXFNIZTTBV-UHFFFAOYSA-N
SMILES C(C(Br)(Br)Br)(O)O
Properties
Chemical formula	C2H3Br3O2
Molar mass	298.756 g·mol−1
Appearance	white crystalline solid with bromal-like smell and taste[1]
Melting point	53.5 °C (128.3 °F; 326.6 K)
Solubility in water	Soluble
Solubility	Soluble in ethanol, Diethyl ether, chloroform and Glycerin
Hazards
GHS labelling:[2]
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H319, H335
Precautionary statements	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

It was also tried as a medication for epilepsy, but was found ineffective.^[1]