Bunitrolol

Bunitrolol is a beta-adrenergic antagonist.^[1]

Bunitrolol

Names
IUPAC name 2-[3-(tert-Butylamino)-2-hydroxypropoxy]benzonitrile
Identifiers
CAS Number	34915-68-9
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL418134
ChemSpider	2379
KEGG	D01444
PubChem CID	2473
UNII	F2613LO055
CompTox Dashboard (EPA)	DTXSID2022701
InChI InChI=1S/C14H20N2O2/c1-14(2,3)16-9-12(17)10-18-13-7-5-4-6-11(13)8-15/h4-7,12,16-17H,9-10H2,1-3H3 Key: VCVQSRCYSKKPBA-UHFFFAOYSA-N InChI=1/C14H20N2O2/c1-14(2,3)16-9-12(17)10-18-13-7-5-4-6-11(13)8-15/h4-7,12,16-17H,9-10H2,1-3H3 Key: VCVQSRCYSKKPBA-UHFFFAOYAU
SMILES CC(C)(C)NCC(COC1=CC=CC=C1C#N)O
Properties
Chemical formula	C14H20N2O2
Molar mass	248.326 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Synthesis

2-Hydroxybenzonitrile (1) is treated with epichlorohydrin and sodium hydroxide to give the epoxide (2). Addition of tert-butylamine completes the synthesis of bunitrolol.^[2]

See also

• Bucindolol
• Epanolol
• Cyanopindolol