Centhaquine

Centhaquine (brand name Lyfaquin) is a cardiovascular drug.^[1] In India, it is approved for the treatment of hypovolemic shock.^[2]

Centhaquine

Clinical data
Trade names	Lyfaquin
Other names	Centhaquin; PMZ-2010; Compound-7173
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2-[2-[4-(3-Methylphenyl)piperazin-1-yl]ethyl]quinoline
CAS Number	57961-90-7
PubChem CID	162163
DrugBank	DB16122
ChemSpider	142413
UNII	QD4VI0J9T5
KEGG	D11974
ChEMBL	ChEMBL4594437
CompTox Dashboard (EPA)	DTXSID40206680
Chemical and physical data
Formula	C22H25N3
Molar mass	331.463 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=CC(=CC=C1)N2CCN(CC2)CCC3=NC4=CC=CC=C4C=C3
InChI InChI=InChI=1S/C22H25N3/c1-18-5-4-7-21(17-18)25-15-13-24(14-16-25)12-11-20-10-9-19-6-2-3-8-22(19)23-20/h2-10,17H,11-16H2,1H3 Key:UJNWGFBJUHIJKK-UHFFFAOYSA-N

Centhaquine is a vasopressor that activates α_2A- and α_2B-adrenoreceptors.^[3] It increases venous return and improves tissue perfusion.