CCL13

Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines.^[1][2] CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5.^[3] Activity of this chemokine has been implicated in allergic reactions such as asthma.^[4] CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-α.

chemokine (C-C motif) ligand 13
Identifiers
Symbol	CCL13
Alt. symbols	SCYA13, MCP-4, NCC-1, SCYL1, CKb10
NCBI gene	6357
HGNC	10611
OMIM	601391
RefSeq	NM_005408
UniProt	Q99616
Other data
Locus	Chr. 17 q11.2
Search for Structures Swiss-model Domains InterPro