CEACAM6

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen (CEA) gene family..^[3]

CEACAM6
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4WTZ, 4WHC, 4YIQ, 4Y8A
Identifiers
Aliases	CEACAM6, CD66c, CEAL, NCA, carcinoembryonic antigen related cell adhesion molecule 6, CEA cell adhesion molecule 6
External IDs	OMIM: 163980; HomoloGene: 130505; GeneCards: CEACAM6; OMA:CEACAM6 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.2 Start 41,750,977 bp[1] End 41,772,211 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell palpebral conjunctiva nasal epithelium mucosa of colon mucosa of sigmoid colon lower lobe of lung mucosa of pharynx epithelium of bronchus trabecular bone bronchial epithelial cell n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding protein heterodimerization activity Cellular component plasma membrane integral component of plasma membrane membrane extracellular space azurophil granule membrane cell surface apical plasma membrane anchored component of membrane Biological process cell-cell signaling leukocyte migration positive regulation of cell population proliferation positive regulation of cell migration neutrophil degranulation homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules signal transduction positive regulation of heterotypic cell-cell adhesion positive regulation of endothelial cell-matrix adhesion via fibronectin negative regulation of anoikis apoptotic process cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4680 n/a Ensembl ENSG00000086548 n/a UniProt P40199 n/a RefSeq (mRNA) NM_002483 n/a RefSeq (protein) NP_002474 n/a Location (UCSC) Chr 19: 41.75 – 41.77 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

See also

• Cluster of differentiation