Cyclic nucleotide-gated channel alpha 2

Cyclic nucleotide gated channel alpha 2, also known as CNGA2, is a human gene encoding an ion channel protein.^[5]

CNGA2
Identifiers
Aliases	CNGA2, CNCA, CNCA1, CNG2, OCNC1, OCNCALPHA, OCNCa, Cyclic nucleotide-gated channel alpha 2, cyclic nucleotide gated channel alpha 2, cyclic nucleotide gated channel subunit alpha 2
External IDs	OMIM: 300338; MGI: 108040; HomoloGene: 32022; GeneCards: CNGA2; OMA:CNGA2 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq28 Start 151,734,746 bp[1] End 151,745,564 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A7.3 Start 71,035,455 bp[2] End 71,053,824 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle left testis Top expressed in olfactory epithelium urethra embryo secondary oocyte zygote primary oocyte entorhinal cortex central gray substance of midbrain superior frontal gyrus thymus More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding cAMP binding calmodulin binding ion channel activity voltage-gated potassium channel activity intracellular cAMP-activated cation channel activity intracellular cGMP-activated cation channel activity cGMP binding Cellular component integral component of membrane membrane Golgi membrane ciliary membrane Golgi-associated vesicle membrane integral component of plasma membrane Biological process response to stimulus regulation of membrane potential ion transport sensory perception of smell ion transmembrane transport transmembrane transport potassium ion transmembrane transport cation transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1260 12789 Ensembl ENSG00000183862 ENSMUSG00000005864 UniProt Q16280 Q62398 RefSeq (mRNA) NM_005140 NM_007724 RefSeq (protein) NP_005131 NP_031750 Location (UCSC) Chr X: 151.73 – 151.75 Mb Chr X: 71.04 – 71.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Cyclic nucleotide-gated ion channel