Collectin-10

Collectin-10, also known as collectin liver 1, is a collectin protein that in humans is encoded by the COLEC10 gene. Its structure is similar to mannan-binding lectin (MBL).^[5]

COLEC10
Identifiers
Aliases	COLEC10, CLL1, CL-34, collectin subfamily member 10, 3MC3, CL-10
External IDs	OMIM: 607620; MGI: 3606482; HomoloGene: 31381; GeneCards: COLEC10; OMA:COLEC10 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.12 Start 118,995,452 bp[1] End 119,108,455 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 D1|15 21.15 cM Start 54,274,170 bp[2] End 54,329,754 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver testicle stromal cell of endometrium gonad right lung gallbladder left ventricle islet of Langerhans apex of heart right coronary artery Top expressed in migratory enteric neural crest cell liver left lobe of liver yolk sac small intestine ileum duodenum abdominal wall jejunum Paneth cell More reference expression data BioGPS n/a
Gene ontology Molecular function mannose binding carbohydrate binding serine-type endopeptidase activity chemoattractant activity monosaccharide binding Cellular component collagen extracellular region extracellular space cytoplasm Golgi apparatus Biological process complement activation proteolysis complement activation, lectin pathway positive chemotaxis cranial skeletal system development developmental process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10584 239447 Ensembl ENSG00000184374 ENSMUSG00000038591 UniProt Q9Y6Z7 Q8CF98 RefSeq (mRNA) NM_006438 NM_001324095 NM_173422 RefSeq (protein) NP_001311024 NP_006429 NP_775598 Location (UCSC) Chr 8: 119 – 119.11 Mb Chr 15: 54.27 – 54.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Collectin liver 1 (CL-L1) show very similar carbohydrate selectivity as MBL. Two other discovered collectins include collectin placenta 1 (CL-P1) and collectin kidney 1 (CL-K1). CL-L1's location found to be on chromosome 8 q23-24.1. Research concluded CL-L1 to be a serum protein.^[6]