CSP-2503

CSP-2503 is a potent and selective 5-HT_1A receptor agonist, 5-HT_2A receptor antagonist, and 5-HT₃ receptor antagonist of the naphthylpiperazine class.^[1] First synthesized in 2003, it was designed based on computational models and QSAR studies.^[2][3] In rat studies, CSP-2503 has demonstrated anxiolytic effects, and thus has been suggested as a treatment for anxiety in humans with a multimodal mechanism of action.^[1]

CSP-2503

Clinical data
ATC code	none
Identifiers
IUPAC name 2-[(4-naphthalen-1-ylpiperazin-1-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS Number	581813-10-7
PubChem CID	10317515
ChemSpider	8492979 Y
UNII	87UKL3XE5X
ChEMBL	ChEMBL285066 Y
Chemical and physical data
Formula	C22H26N4O2
Molar mass	378.476 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C4N5CCCC5C(=O)N(CN3CCN(c2c1ccccc1ccc2)CC3)C4
InChI InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2 Y Key:CTZWGZSINBFHFD-UHFFFAOYSA-N Y
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See also

• Naphthylpiperazine
• S-14,671
• S-14,506