CUMYL-THPINACA

CUMYL-THPINACA
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B; Illegal in China and Sweden;
Identifiers
	IUPAC name 1-(oxan-4-ylmethyl)-N-(2-phenylpropan-2-yl)indazole-3-carboxamide;
CAS Number	1400742-50-8 ;
PubChem CID	86273679;
ChemSpider	48057932;
UNII	6R5GTC3QVB;
CompTox Dashboard (EPA)	DTXSID401032565 ;
Chemical and physical data
Formula	C23H27N3O2
Molar mass	377.488 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NC(C)(C)C1=CC=CC=C1)C2=NN(CC3CCOCC3)C4=C2C=CC=C4;
	InChI InChI=1S/C23H27N3O2/c1-23(2,18-8-4-3-5-9-18)24-22(27)21-19-10-6-7-11-20(19)26(25-21)16-17-12-14-28-15-13-17/h3-11,17H,12-16H2,1-2H3,(H,24,27); Key:HINCNLQQLQFMRD-UHFFFAOYSA-N;

CUMYL-THPINACA (also known as SGT-42) is an indazole-3-carboxamide based synthetic cannabinoid.^[1]^[2] CUMYL-THPINACA acts as a potent agonist for the cannabinoid receptors, with approximately 6x selectivity for CB₁, having an EC₅₀ of 0.1nM for human CB₁ receptors and 0.59nM for human CB₂ receptors.^[3]

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