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Calcium-activated potassium channel beta subunit

Protein family From Wikipedia, the free encyclopedia

Calcium-activated potassium channel beta subunit
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In molecular biology, the calcium-activated potassium channel beta subunit is a family of proteins comprising the beta subunits of calcium-activated potassium channels.

Quick Facts CaKB, Identifiers ...

The functional diversity of potassium channels can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. The beta subunit (which is thought to possess 2 transmembrane domains) increases the calcium sensitivity of the BK channel.[1] It does this by enhancing the time spent by the channel in burst-like open states. However, it has little effect on the durations of closed intervals between bursts, or on the numbers of open and closed states entered during gating.[2]

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