Carboxynorspermidine synthase

Carboxynorspermidine synthase (EC 1.5.1.43, carboxynorspermidine dehydrogenase, carboxyspermidine dehydrogenase, CASDH, CANSDH) is an enzyme with systematic name carboxynorspermidine:NADP⁺ oxidoreductase.^[1][2][3] This enzyme catalyses the following chemical reactions

(1) carboxynorspermidine + H₂O + NADP⁺ ${\displaystyle \rightleftharpoons }$ L-aspartate 4-semialdehyde + propane-1,3-diamine + NADPH + H⁺

(2) carboxyspermidine + H₂O + NADP⁺ ${\displaystyle \rightleftharpoons }$ L-aspartate 4-semialdehyde + putrescine + NADPH + H⁺

Carboxynorspermidine synthase
Identifiers
EC no.	1.5.1.43
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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The reaction takes place in the opposite direction.