Carotenoid isomerooxygenase

Carotenoid isomerooxygenase (EC 1.13.11.65, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing).^[1] This enzyme catalyses the following chemical reaction

zeaxanthin + O₂ ${\displaystyle \rightleftharpoons }$ (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal

Carotenoid isomerooxygenase
Identifiers
EC no.	1.13.11.65
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal .