Cepharanthine

Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania.^[1] Due to these modalities, it has been shown effective against HTLV in lab research. ^[2] Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. ^[3]

Cepharanthine

Clinical data
Other names	Cepharantin, O-Methylcepharanoline
AHFS/Drugs.com	International Drug Names
ATC code	none
Identifiers
IUPAC name (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene
CAS Number	481-49-2
PubChem CID	10206
ChemSpider	9791
UNII	7592YJ0J6T
ChEMBL	ChEMBL449782
CompTox Dashboard (EPA)	DTXSID6045957
ECHA InfoCard	100.208.632
Chemical and physical data
Formula	C37H38N2O6
Molar mass	606.719 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3
InChI InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1 Key:YVPXVXANRNDGTA-WDYNHAJCSA-N