Cerefolin

Cerefolin is a prescription medication made by Pamlab that contains 5.635 mg of folate as L-methylfolate, 1 mg of vitamin B₁₂ as methylcobalamin, 50 mg of vitamin B₂ as riboflavin, and 5 mg of vitamin B₆ as pyridoxine. It is approved by the U.S. Food and Drug Administration for the treatment or prevention of vitamin deficiencies.^[1]

Cerefolin

Combination of
folate	as L-methylfolate
vitamin B12	as methylcobalamin
vitamin B2	as riboflavin
vitamin B6	as pyridoxine
Clinical data
Other names	Denovo, Deplin, Duleek-DP, Elfolate, L-Methylfolate Formula, L-Methylfolate Forte, Vilofane-DP, XaQuil XR, Zervalx
AHFS/Drugs.com	Consumer Drug Information
Pregnancy category	Not assigned
Routes of administration	Oral
Drug class	Vitamin supplement
Legal status
Legal status	AU: S4 (Prescription only) CA: ℞-only UK: POM (Prescription only) US: ℞-only and OTC

"Cerefolin NAC" contains L-methylfolate (as Metafolin) 5.6 mg, methylcobalamin 2 mg, N-acetylcysteine 600 mg.^[2]

Risks

Cerefolin is a potentially harmful drug. Adverse effects can include diarrhea, Hand-foot syndrome, Rashes, Renal stones, Constipation, headaches, flushing, and swelling.^[2]