Chakragati mouse

Chakragati mouse (ckr) is an insertional transgenic mouse mutant (Mus musculus) displaying hyperactive behaviour and circling. It is also deficient in prepulse inhibition, latent inhibition^[1] and has brain abnormalities such as lateral ventricular enlargement^[2] that are typical to endophenotypic models of schizophrenia, which make it useful in screening for antipsychotic drug candidates.^[3] The mouse is currently licensed by Chakra Biotech.