Chloride channel blocker

A chloride channel blocker is a type of drug which inhibits the transmission of ions (Cl⁻) through chloride channels.

Niflumic acid is a chloride channel blocker that has been used in experimental scientific research.^[1] Another example is anthracene-9-carboxylic acid, a potent blocker of the CLCN1-type chloride channel found in skeletal muscle, which is used to study animal models of myotonia congenita.^[2]

Some antagonists of glycine receptors and GABAA receptors also act as chloride channel blockers.

See also

• Chloride channel opener