Chlorite dismutase

Chlorite dismutase, also known as Chlorite O₂-lyase (EC 1.13.11.49), is an enzyme that catalyzes the chemical reaction

ClO⁻
₂ → Cl⁻ + O₂

chlorite dismutase
Identifiers
EC no.	1.13.11.49
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Reactions that generate oxygen molecules are exceedingly rare in biology and difficult to mimic synthetically. Perchlorate - respiring bacteria enzymatically detoxify chlorite, ClO⁻
₂, the end product of the perchlorate, ClO⁻
₄, respiratory pathway, by converting it to dioxygen, O₂, and chloride, Cl⁻.^[1] Chlorite dismutase is a heme-containing protein, but it bears no structural or sequence relationships with known peroxidases or other heme proteins and is part of a large family of proteins with more than one biochemical function.