Cholest-4-en-3-one 26-monooxygenase

Cholest-4-en-3-one 26-monooxygenase (EC 1.14.13.141, CYP125, CYP125A1, cholest-4-en-3-one 27-monooxygenase) is an enzyme with systematic name cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating).^[1][2][3][4] This enzyme catalyses the following chemical reaction

cholest-4-en-3-one + NADH + H⁺ + O₂ ${\displaystyle \rightleftharpoons }$ 26-hydroxycholest-4-en-3-one + NAD⁺ + H₂O

Cholest-4-en-3-one 26-monooxygenase
Identifiers
EC no.	1.14.13.141
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Cholest-4-en-3-one 26-monooxygenase is a heme thiolate (P450) enzyme.