Clogestone

Clogestone (INN, BAN), also known as chlormadinol or as 3β,17α-dihydroxy-6-chloropregna-4,6-diene-20-one,^[1] is a steroidal progestin that was synthesized in 1964 and was investigated as a progestin-only contraceptive but was never marketed.^[2][3] A diacetate ester, clogestone acetate, also exists and similarly was never marketed.^[2]

Clogestone

Clinical data
Other names	Chlormadinol
Identifiers
IUPAC name 1-[(1S,2R,5S,10R,11S,14R,15S)-8-chloro-5,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,8-dien-14-yl]ethan-1-one
CAS Number	20047-75-0
PubChem CID	20055454
ChemSpider	16736893
UNII	0I88K7V2TF
CompTox Dashboard (EPA)	DTXSID60173865
Chemical and physical data
Formula	C21H29ClO3
Molar mass	364.91 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(CCC34C)O)Cl)C)O
InChI InChI=1S/C21H29ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h10-11,13-16,24-25H,4-9H2,1-3H3/t13-,14+,15-,16-,19+,20-,21-/m0/s1 Key:WZTUZRFSDWXDRM-IAGOJMRCSA-N

See also

• Acetomepregenol
• Butagest
• Mecigestone